There will be a lot of spoilers and I do recommenced to experience this game yourself.
But if you are just playing to get all achievements this guide will be useful.
I will walk you through how to collect all the achievements in this game.
Start up the game, make a qualia and enter.
core mechanicsSteps
Break two different blocks using Left Click.

Press E to open your Inventory.
Navigate to the Apotheosis tab.
Place the two blocks into any two of the six slots in the fusion circle.
Click the grey button on the right to start the fusion.

You will receive Apotheosis α as the result.
There are two ways to obtain a projectile wand.
Sometimes you can find a Manikin holding a wand.
If you attack it quickly, you can kill it before the wand loses all of its durability and obtain it.
Manikins are also great for obtaining useful early materials such as:
• String
• Sticks
• Cut Wood Planks
These are very useful for fusing your first equipment.
The easiest way I found is by using Magnitite and Sticks.
First fuse:
Magnitite + Stick
This creates a Key Axe.

Then fuse:
Magnitite + Key axe
to create a Ball Wand.

After obtaining and using the wand you will receive the achievement:
Archangel α
Sticks
• Break tree leaves
• Fuse wooden pick axe with anything
Magnitite
• Mine Magnitite Ore Blocks
(If I find the ore block again I will upload a screenshot here.)

The Glider Glove can be obtained in two main ways:
Sometimes Glider Gloves are found inside cardboard boxes. Keep an eye out while exploring.
Feathers tend to fuse into a Glider Glove. You can obtain feathers by:
• Killing Noots

• Collecting wool from Sheep and fusing it with sticks to create feathers

Once you have feathers, fuse them to create a Glider Glove:

Use the glove with Right-Click to fly.
Using the Glider Glove will unlock the achievement:
Virtue α

To use a Hookshot, you first need to obtain or craft one.
The easiest method I’ve found is fusing:
• A metal-like block
• A string
You can mine metal blocks in your personal Clonaqualia dimension.
(To make a Clonaqualia block, fuse a Rejuvenation Anchor with almost any item, then place it and right-click to enter.)
Once you have the materials, fuse them to create a Hookshot:

• Hold the Hookshot in your hand.
• Hold Right-Click to pull yourself toward an object.
Using the Hookshot unlocks the achievement:
Virtue β
You can combine the momentum of the Hookshot with the Glider Glove to travel long distances along the Y-axis.

You keep your inventory on death.
You can do this one whenever.
try:
Attacking neutral creatures.
Drowning or taking fall damage.
This guide explains a simple way to unlock the achievement and obtain a
useful capsule early.
First, find materials that behave like organic blocks.
Fuse two different dirt-type materials to create a grass block.
Examples:
• Dirt + Sand • Dirt + another Dirt type • Black Sand Block + Dirt Block
(the one I used)

There are many combinations that can result in a grass block.
Next you need a creature part.
Look for materials dropped by creatures such as: • Segments • Glands •
Eyes
If you find a passive creature, try killing it to see what it drops.

In this example I used a segment from a Wyrm, but its gland or eye
should also work.
Fuse:
Grass Block + Creature Part
This should preferably produce a Bubblebear Egg.

Now combine the same egg with:
• Grass Block or • Dirt Block or another organic block
This should result in the item shown below.

You should receive a:
Fruit Femme Capsule
This will unlock the achievement:
Apotheosis β
I recommend keeping this capsule because it makes several other
achievements easier.
It provides a steady supply of food and helps unlock:
• Apotheosis γ • Dominion α • Bubblebear Massacre • Dominion β
Some items seem to have a counterpart relationship. For example:
Fruit Femme Capsule ↔ Bubblebear
Adding extra blocks while fusing with a counterpart can sometimes
increase the chance of producing more capsules.
A good strategy is:
1. Keep fusing capsules until you have several.
2. Spawn multiple Femme Fruits.
3. Kill them to obtain: • Nuts • Seeds • Style Seeds
4. Keep at least one capsule so you can continue the fusion loop.
This creates a sustainable resource cycle.
The Style Seeds can be grown into accessories that provide stats or
special effects.
Fruit Seeds can grow into:
• Nuts • Occasionally a Rejuvenation Anchor
Fuse a Rejuvenation Anchor into a Clonaqualia Block.
Right-clicking this block lets you enter your personal qualia (similar
to a pocket dimension).
This is a great place to plant and manage all your seeds safely.
Fuse:
Nuts + Rejuvenation Anchor
This produces a:
Revelation Fruit
It heals 10 HP.
If you keep farming seeds, you will eventually have an abundance of
these healing fruits.

By now, you should have plenty of Fruit Seeds and Style Seeds from defeating Femme Fruits.
I suggest planting them in your Pocket Dimension for easy management.
To plant a seed:
1. Right-click the ground while holding the seed.
2. Wait until you see a pearl appear. They should look like this:

You can harvest a fully-grown nut by left-clicking on it.
Harvesting the plant will unlock the achievement:
Dominion β
You will need a Faith Wand to perform this action.
There are multiple ways to fuse a Faith Wand.
If you still have Magnitite from making the Ball Wand, it should be straightforward.
1. Take the Key Axe:

2. Fuse the Key Axe with a Bone or other “bone-like” items:

Right-click while holding the Faith Wand:

Using the wand will unlock the achievement:
Archangel β
If you fuse the Faith Wand with another bone, you can create a Hate Wand.
• Deals damage based on hate stat, especially useful if you’ve defeated many capsule creatures.
It has been nerfed 🙁
• Warning: The AoE explosion can also harm you if you are within range.

If you followed along with the farming steps earlier, you should already have the materials needed for this.
You can create a Rejuvenation Fruit by fusing Nuts with a Rejuvenation Anchor.

Fusing these items will create a divine artifact and unlock the achievement.
This unlocks the achievement:
Apotheosis γ

There are two ways to complete this achievement.
You can craft a bomb using the recipe shown below:

Another method is to kill an Alach, which can drop up to 30 bombs.
To create an Alach capsule instead:
Golem + Bone = 2 Goo
Goo + Petal Block (almost any block works) = Gel
Gel + Goo = 2 Vyrm
Vyrm + Petal Block = Alach

Using a bomb will unlock the achievement:
Archangel γ

To complete this achievement, you need to rename a vermin.
You will first need a Pencil.
You can craft one using the Glider Glove you already obtained.
Fuse:
Glider Glove + Stick = Pencil

Hold the pencil and right-click on a vermin.

Doing this will unlock the achievement:
Dominion γ

Now for one of the main mechanics of the game: Tiamana Leylines.
By this point you should be geared up enough to start clearing them.
To access Leylines, you will need to level up. You gain experience by:
• Killing creatures
• Fusing items
When you level up, choose the Tiamana Leyline option.

You will want to stock up on pendants whenever possible.
If you complete every leyline without failing, you want to obtain a total of 12.
Selecting the leyline option rewards you with a Pendant.

Hold the pendant and right-click to activate it.
It will point you toward the closest leyline from your current position.
Find the leyline.
Doing this will unlock the achievement:
Angel γ

This achievement is a bit of a chore. I never encountered the bird naturally during my playtime, so after about two hours of fusing creatures I eventually fused its capsule instead.

Below is the recipe chain required to create the capsule.

You will need the following capsules:
• Meeshuu
• Worm
• Vyrm
• Wildebeest
• Preta
• Alach
Tip: Petal blocks make crafting capsules easier since they tend to fuse into capsule-type results.
Fuse:
Petal Block (almost any other block) + Accelo (drop from the big white spider) = Blasphemy

Accelo + Blasphemy = Meeshuu

Make 2 Meeshuu for later steps.
Petal Block + Brick = Golem
bubblebear + a lot of bircks also works
Make 2 Golems for later.

Golem + Meeshuu = Preta

You will need 4 Vyrm total.
Golem + Bone = 2 Goo

Goo + Petal Block (almost any block works) = Gel

Gel + Goo = 2 Vyrm

Vyrm + Petal Block (almost any block)

Vyrm + Bee = Worm

For Bee:
Vyrm + Golem = Bee

Alternate Bee recipe, keep fusing capsules you get from Femme Fruits or Bubble Bears.
bubble bear + femme fruit = purple bubble bear
bubble bear + femme fruit + purple bubble bear = sheep
bubble bear + femme fruit + purple bubble bear + sheep = koi
bubble bear + femme fruit + purple bubble bear + sheep + koi = bee

Vyrm + Alach = 2 Wildebeest

Fuse all six capsules together and defeat the creature that spawns.
It will drop the Hand Wand.
This unlocks the achievement:
Dominion δ